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Year : 2018  |  Volume : 5  |  Issue : 2  |  Page : 51-59

Cardiorenal and hepatorenal syndrome

1 Sr. Consultant, PICU, Nelson Mother and child care Hospital, Nagpur, India
2 Consultant, PICU, Nelson Mother and child care Hospital, Nagpur, India
3 Fellow, PICU, Nelson Mother and child care Hospital, Nagpur, India
4 Chief, Advanced Pediatric Critical Care Centre & Head, Dept of Pediatrics, Wanless Hospital, Miraj, India

Correspondence Address:
Anand Bhutada
Consultant Pediatric & Neonatal Intensivist, Central India's Child Hospital and Research Institute, Shreevardhan Complex, Ramdaspeth, Nagpur 440012
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Source of Support: None, Conflict of Interest: None

DOI: 10.21304/2018.0502.00374

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Cardiorenal syndrome(CRS) is an interdependent involvement of the heart and the kidney that leads to high morbidity, recurrent readmissions and grave prognosis. Early use of slow high-dose intravenous diuretics, dialysis with ultrafiltration for treatment of congestion, inotropes and left ventricular assistant device to stabilize the hemodynamics and maintenance of the renal perfusion are the vital component for a short period of time. Hepatorenal syndrome (HRS) is a unique form of functional renal failure associated with progressive liver failure. It carries worst prognosis among all causes of renal failure in children with liver disease. Liver transplantation is the definitive treatment of HRS. Vasoconstrictor therapy with albumin and Renal replacement therapy are used as a bridge to liver transplant for patients who are unresponsive to medical therapy.

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